Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.32 |
| ▸ | KCNA1 | Q09470 | 3/20 | 0.32 |
| ▸ | KCNAB1 | Q14722 | 3/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923115 | 0.91 | P2RY12 (0.49) | P2RY12MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL13638364 | 0.90 | P2RY12 (0.40) | P2RY12BRD4CREBBPMEN1KMT2A | |
| SCHEMBL12177059 | 0.88 | P2RY12 (0.39) | P2RY12BRD4CREBBPMEN1KMT2A | |
| SCHEMBL13638556 | 0.88 | P2RY12 (0.35) | P2RY12BRD4CREBBPMEN1KMT2A | |
| SCHEMBL9922807 | 0.87 | P2RY12 (0.40) | P2RY12MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14113565 | 0.85 | GAA (0.38) | P2RY12BRD4CREBBPMEN1KMT2A | |
| SCHEMBL13638361 | 0.83 | KMT2A (0.50) | BRD4CREBBPMEN1KMT2AGAA | |
| SCHEMBL9923113 | 0.83 | P2RY12 (0.51) | P2RY12MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL9922425 | 0.82 | BRD4 (0.37) | P2RY12BRD4CREBBPMEN1KMT2A | |
| SCHEMBL9922318 | 0.82 | P2RY12 (0.45) | P2RY12MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |