Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KCNA1 | Q09470 | 4/20 | 0.33 |
| ▸ | KCNAB1 | Q14722 | 4/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160790 | 0.90 | P2RY12 (0.43) | P2RY12MEN1KMT2ASMN1; SMN2KCNA1 | |
| SCHEMBL9922839 | 0.88 | P2RY12 (0.35) | P2RY12GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12161524 | 0.86 | PTGER3 (0.37) | P2RY12KCNA1KCNAB1 | |
| SCHEMBL14113565 | 0.85 | GAA (0.38) | BRD4CREBBPP2RY12GAAMEN1 | |
| SCHEMBL9922444 | 0.84 | BRD4 (0.34) | BRD4CREBBPP2RY12MEN1KMT2A | |
| SCHEMBL13638361 | 0.83 | KMT2A (0.50) | BRD4CREBBPGAAMEN1KMT2A | |
| SCHEMBL13638362 | 0.82 | P2RY12 (0.40) | BRD4CREBBPP2RY12GAAMEN1 | |
| SCHEMBL13638364 | 0.82 | P2RY12 (0.40) | BRD4CREBBPP2RY12GAAMEN1 | |
| SCHEMBL9922482 | 0.81 | P2RY12 (0.39) | P2RY12MEN1KMT2ASMN1; SMN2KCNA1 | |
| SCHEMBL12177620 | 0.80 | BRD4 (0.37) | BRD4CREBBPP2RY12GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | BRD4 3064/4885CREBBP 3041/4885P2RY12 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.