Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 5/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.37 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922817 | 0.92 | FBP1 (0.41) | FBP1NLRP3KMT2AMEN1GAA | |
| SCHEMBL9922401 | 0.91 | NLRP3 (0.39) | FBP1NLRP3KMT2AMEN1USP2 | |
| SCHEMBL9922472 | 0.88 | KMT2A (0.41) | FBP1NLRP3KMT2AMEN1GAA | |
| SCHEMBL12161602 | 0.88 | KMT2A (0.41) | FBP1NLRP3KMT2AMEN1USP2 | |
| SCHEMBL12177069 | 0.87 | BRD4 (0.35) | FBP1NLRP3KMT2AMEN1USP2 | |
| SCHEMBL14113602 | 0.86 | BRD4 (0.35) | FBP1NLRP3KMT2AMEN1USP2 | |
| SCHEMBL14228633 | 0.86 | BRD4 (0.34) | FBP1NLRP3KMT2AMEN1USP2 | |
| SCHEMBL13638555 | 0.84 | P2RY12 (0.38) | FBP1NLRP3KMT2AMEN1USP2 | |
| SCHEMBL13638556 | 0.84 | P2RY12 (0.35) | FBP1NLRP3KMT2AMEN1USP2 | |
| SCHEMBL14228332 | 0.84 | HRH3 (0.35) | CREBBPBRD4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |