Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228483 | 0.88 | GLA (0.35) | GLAL3MBTL1PPARGMAPTKMT2A | |
| SCHEMBL12177061 | 0.87 | KMT2A (0.36) | PPARGTP53TSHRMAPTKMT2A | |
| SCHEMBL12177258 | 0.86 | HPD (0.34) | GLAL3MBTL1PPARGMAPTKMT2A | |
| SCHEMBL14228334 | 0.85 | TERT (0.39) | — | |
| SCHEMBL14228338 | 0.84 | TSHR (0.40) | L3MBTL1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL9922167 | 0.81 | P2RY12 (0.52) | GLAL3MBTL1PPARGTP53ALDH1A1 | |
| SCHEMBL12177247 | 0.81 | GLA (0.52) | GLAL3MBTL1PPARGTP53ALDH1A1 | |
| SCHEMBL13638385 | 0.81 | GLA (0.36) | GLAL3MBTL1PPARGALDH1A1KMT2A | |
| SCHEMBL13182890 | 0.80 | POLB (0.34) | GLAL3MBTL1PPARGHPD | |
| SCHEMBL12177317 | 0.79 | POLB (0.35) | PPARGTP53ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |