Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638585 | 0.92 | TERT (0.35) | GLAHPDMEN1KMT2AL3MBTL1 | |
| SCHEMBL13638542 | 0.89 | PPARG (0.39) | PPARGNOD1P2RY12 | |
| SCHEMBL14228483 | 0.87 | GLA (0.35) | GLAHPDMEN1KMT2AL3MBTL1 | |
| SCHEMBL13638559 | 0.84 | HPD (0.34) | GLAHPDMEN1KMT2AL3MBTL1 | |
| SCHEMBL9923210 | 0.83 | P2RY12 (0.40) | GLAHPDMEN1KMT2AL3MBTL1 | |
| SCHEMBL14228334 | 0.82 | TERT (0.39) | — | |
| SCHEMBL9923213 | 0.81 | P2RY12 (0.49) | GLAHPDMEN1KMT2AL3MBTL1 | |
| SCHEMBL14228338 | 0.81 | TSHR (0.40) | L3MBTL1ALDH1A1 | |
| SCHEMBL13638648 | 0.81 | GLA (0.48) | GLAHPDKMT2AL3MBTL1PPARG | |
| SCHEMBL14113540 | 0.81 | PPARG (0.40) | PPARGP2RY12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |