SCHEMBL1363871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3400356	0.86	MGLL (0.49)	MGLLFAAHGPR119
	SCHEMBL6397967	0.86	MGLL (0.64)	MGLLGPR119CETPYAP1KDM4E
	SCHEMBL1364206	0.85	HDAC1 (0.45)	HDAC1FAAHGPR119SLC2A1YAP1
	SCHEMBL12053524	0.84	HDAC1 (0.44)	HDAC1FAAHGPR119SLC2A1YAP1
	SCHEMBL2678587	0.80	GPR119 (0.53)	FAAHGPR119SLC2A1KDM4EPKM
	SCHEMBL21264864	0.79	MET (0.53)	HDAC1GPR119SLC2A1
	SCHEMBL29650137	0.78	GPR119 (0.52)	MGLLHDAC1FAAHGPR119
	SCHEMBL18280088	0.78	GPR119 (0.54)	MGLLGPR119CETP
	SCHEMBL17700334	0.78	GPR119 (0.52)	MGLLHDAC1FAAHGPR119
	SCHEMBL1363667	0.78	KDM4E (0.48)	GPR119YAP1KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.