Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638718 | 0.79 | MEN1 (0.38) | MAPTCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL8986302 | 0.77 | MEN1 (0.36) | KMT2AMEN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL14282584 | 0.62 | AKR1C3 (0.44) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8986303 | 0.61 | LMNA (0.37) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8986306 | 0.58 | AKR1C3 (0.40) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL12629680 | 0.57 | KMT2A (0.36) | KMT2AMEN1POLB | |
| SCHEMBL8986301 | 0.57 | AKR1C3 (0.38) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4388274 | 0.57 | MLKL (0.31) | — | |
| SCHEMBL13638717 | 0.57 | AKR1C3 (0.38) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11922326 | 0.57 | AKR1C3 (0.38) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304561-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-11-06 | — | — | US | disclosed |