Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638716 | 0.79 | MAPT (0.32) | MEN1KMT2ACYP2D6MAPTCYP1A2 | |
| SCHEMBL8986300 | 0.70 | AKR1C3 (0.38) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL10146241 | 0.67 | GAA (0.39) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL12653626 | 0.66 | — | — | |
| SCHEMBL270836 | 0.65 | SLC6A2 (0.44) | KMT2ACES2CES1HDAC1HDAC8 | |
| SCHEMBL5865581 | 0.65 | KMT2A (0.47) | KMT2ACES2CES1HDAC1HDAC8 | |
| SCHEMBL29912766 | 0.65 | HDAC1 (0.43) | KMT2ACYP2D6MAPTTP53CES2 | |
| SCHEMBL14282583 | 0.64 | MLKL (0.40) | KMT2ACYP2D6CYP2C19LMNA | |
| SCHEMBL13692751 | 0.63 | SLC6A2 (0.35) | MEN1KMT2A | |
| SCHEMBL5666091 | 0.61 | TDP1 (0.44) | MEN1KMT2ACYP2D6LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304561-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-11-06 | — | — | US | disclosed |