Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14322127 | 0.89 | SLC6A2 (0.32) | KMT2ACYP19A1 | |
| SCHEMBL14282583 | 0.81 | MLKL (0.40) | KMT2ACYP19A1LMNAMLKL | |
| SCHEMBL270836 | 0.80 | SLC6A2 (0.44) | KMT2A | |
| SCHEMBL20173417 | 0.80 | MLKL (0.41) | GAAKMT2ACHRNA7KDM4EACHE | |
| SCHEMBL17906216 | 0.79 | ENPP3 (0.41) | NISCH | |
| SCHEMBL12653626 | 0.79 | — | — | |
| SCHEMBL14528752 | 0.79 | AURKA (0.34) | MEN1KMT2ATDP1MAPT | |
| SCHEMBL8737796 | 0.79 | — | — | |
| SCHEMBL19633885 | 0.79 | ESR1 (0.38) | GAAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL469142 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005806-B2 | Metalporphyrin complex, preparation method therefor and method for preparing polycarbonate | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-06-26 | — | — | US | disclosed |
| US-10005806-B2 | Metalporphyrin complex, preparation method therefor and method for preparing polycarbonate | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-06-26 | — | — | US | disclosed |
| EP-3246331-A1 | QUINONE-METHIDE PRECURSORS WITH BODIPY CHROMOPHORE, METHOD OF PREPARATION, BIOLOGICAL ACTIVITY AND APPLICATION IN FLUORESCENT LABELING | Rudjer Boskovic Institute (HR) | 2017-11-22 | — | — | EP | disclosed |
| US-20160194346-A1 | METALPORPHYRIN COMPLEX, PREPARATION METHOD THEREFOR AND METHOD FOR PREPARING POLYCARBONATE | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-07-07 | — | — | US | disclosed |
| US-20160194346-A1 | METALPORPHYRIN COMPLEX, PREPARATION METHOD THEREFOR AND METHOD FOR PREPARING POLYCARBONATE | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-07-07 | — | — | US | disclosed |
| US-8980565-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980565-B2 | Porphyrinic compounds for use in flow cytometry | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140106367-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-04-17 | — | — | US | disclosed |
| US-8530459-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-09-10 | — | — | US | disclosed |
| US-8524892-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-09-03 | — | — | US | disclosed |
| US-7582751-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090198049-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-08-06 | — | — | US | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| WO-2007018808-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007018807-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, DHPS, POR | GAA 3155/4885MEN1 592/4885KMT2A 1827/4885 |
| US-20160194346-A1 | METALPORPHYRIN COMPLEX, PREPARATION METHOD THEREFOR AND METHOD FOR PREPARING POLYCARBONATE | CYP4F11, CYP4F12, POR | GAA 3904/4885MEN1 2583/4885KMT2A 1860/4885 |
| US-10005806-B2 | Metalporphyrin complex, preparation method therefor and method for preparing polycarbonate | CYP4F11, CYP4F12, POR | GAA 3904/4885MEN1 2583/4885KMT2A 1860/4885 |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, HMBS, CYC1 | GAA 3440/4885MEN1 692/4885KMT2A 1733/4885 |
| US-20090198049-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | PPOX, HMBS, CYC1 | GAA 3440/4885MEN1 692/4885KMT2A 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.