Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950856 | 0.76 | ACHE (0.51) | ALDH1A1MEN1KMT2AACHECYP3A4 | |
| SCHEMBL13163095 | 0.74 | ALDH1A1 (0.45) | AAK1ALDH1A1LMNATSHRLRRK2 | |
| SCHEMBL263756 | 0.74 | LTA4H (0.49) | LTA4HALDH1A1ACHEPIK3CACYP3A4 | |
| SCHEMBL15106443 | 0.73 | TYR (0.56) | ALDH1A1MEN1LMNAKMT2ACYP3A4 | |
| SCHEMBL3208009 | 0.72 | PRKDC (0.63) | ALDH1A1MEN1LMNAKMT2APIK3CD | |
| SCHEMBL1203109 | 0.72 | CYP2D6 (0.46) | LTA4HALDH1A1ACHEPIK3CDCYP3A4 | |
| SCHEMBL6476590 | 0.69 | GAA (0.41) | LTA4HAAK1ALDH1A1LMNACYP3A4 | |
| SCHEMBL13163125 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL15418248 | 0.68 | CSF1R (0.39) | LTA4HACHECYP3A4TSHRCYP2C19 | |
| SCHEMBL19500870 | 0.68 | ACHE (0.63) | MEN1KMT2AACHECYP3A4OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |