Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634619 | 0.93 | SCN9A (0.43) | PDE4DIRAK4SCDCHEK1SLC5A7 | |
| SCHEMBL13638995 | 0.91 | SCD (0.43) | PDE4DSCDHPGDGPR6 | |
| SCHEMBL13634606 | 0.89 | IRAK4 (0.43) | PDE4DIRAK4SCDCHEK1SLC5A7 | |
| SCHEMBL13634679 | 0.89 | IRAK4 (0.43) | PDE4DIRAK4SCDCHEK1SLC5A7 | |
| SCHEMBL13638763 | 0.85 | SCD (0.42) | SCDHPGDGPR6 | |
| SCHEMBL13634648 | 0.85 | MAP3K7 (0.51) | IRAK4CHEK1GPR6 | |
| SCHEMBL13634680 | 0.83 | POLB (0.42) | PDE4DIRAK4SCDCHEK1SLC5A7 | |
| SCHEMBL13638935 | 0.82 | SCD (0.44) | IRAK4SCDCHEK1HPGDGPR6 | |
| SCHEMBL13634702 | 0.81 | HRH3 (0.41) | IRAK4SCDCHEK1GPR6 | |
| SCHEMBL13634803 | 0.81 | IRAK4 (0.43) | PDE4DIRAK4SCDCHEK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |