Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638838 | 0.84 | HPGDS (0.54) | NPC1RAB9AKDM1ASMN1; SMN2HPGD | |
| SCHEMBL13162001 | 0.83 | NPC1 (0.55) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13162551 | 0.81 | NPC1 (0.52) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21349122 | 0.78 | KDM1A (0.58) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13162265 | 0.78 | ALDH1A1 (0.51) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13638856 | 0.76 | HPGDS (0.54) | NPC1RAB9AKDM1ASMN1; SMN2HPGD | |
| SCHEMBL2770068 | 0.75 | ALDH1A1 (0.61) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12124399 | 0.74 | HPGD (0.71) | NPC1RAB9ACYP2C19KDM1ASMN1; SMN2 | |
| SCHEMBL13162870 | 0.74 | SMN1; SMN2 (0.50) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19175555 | 0.74 | NPC1 (0.52) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |