Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638838 | 0.90 | HPGDS (0.54) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13163162 | 0.84 | HPGDS (0.57) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13161909 | 0.82 | HPGDS (0.56) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29798407 | 0.81 | HPGDS (0.57) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13162029 | 0.81 | HPGDS (0.57) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13161912 | 0.80 | HPGDS (0.56) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13162266 | 0.80 | ALDH1A1 (0.57) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL13638862 | 0.77 | NTRK1 (0.39) | HPGDSRAB9ANPC1KDM1APDE4B | |
| SCHEMBL13162264 | 0.77 | HPGDS (0.53) | HPGDSRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL22725997 | 0.76 | HPGDS (0.52) | HPGDSRAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |