Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163132 | 0.86 | POLB (0.52) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13163950 | 0.85 | MCHR1 (0.55) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13162753 | 0.83 | ALDH1A1 (0.49) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13638845 | 0.80 | BMPR1B (0.47) | KMT2ASMN1; SMN2MEN1POLBHRH3 | |
| SCHEMBL13638862 | 0.79 | NTRK1 (0.39) | NPC1RAB9AHDAC6 | |
| SCHEMBL13162043 | 0.78 | KDM4E (0.59) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13162666 | 0.78 | POLB (0.50) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13162881 | 0.78 | KDM4E (0.56) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13270756 | 0.78 | POLB (0.52) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13162375 | 0.78 | KDM4E (0.55) | KDM4EKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |