Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162025 | 0.87 | TSHR (0.43) | NTRK1KDM1AGRM1HPGDSHDAC11 | |
| SCHEMBL13162538 | 0.86 | NTRK1 (0.40) | NTRK1KDM1AGRM1HPGDSHDAC11 | |
| SCHEMBL13163923 | 0.83 | ALDH1A1 (0.48) | NTRK1KDM1ANPC1RAB9ABRD4 | |
| SCHEMBL13638844 | 0.79 | KDM4E (0.47) | NPC1RAB9AHDAC6 | |
| SCHEMBL13638856 | 0.77 | HPGDS (0.54) | KDM1AHPGDSNPC1RAB9APDE4B | |
| SCHEMBL13638929 | 0.76 | TSHR (0.44) | NTRK1KDM1ANPC1RAB9ABRD4 | |
| SCHEMBL13162671 | 0.76 | TSHR (0.44) | NTRK1KDM1ANPC1RAB9ABRD4 | |
| SCHEMBL13634274 | 0.73 | ALDH1A1 (0.50) | NTRK1NPC1RAB9ABRD4SMYD3 | |
| SCHEMBL13638807 | 0.73 | ALDH1A1 (0.47) | NPC1RAB9A | |
| SCHEMBL13638947 | 0.71 | IRAK4 (0.42) | NTRK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |