Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12012867 | 0.80 | SMN1; SMN2 (0.40) | CYP1A2HPGDALOX15MAPTKDM4E | |
| SCHEMBL917999 | 0.80 | CDK1 (0.56) | HRH3PRKCIACHEHDAC8HDAC6 | |
| SCHEMBL27814635 | 0.78 | HRH3 (0.54) | HRH3PRKCIACHEHDAC8HDAC6 | |
| SCHEMBL13638875 | 0.78 | HRH3 (0.42) | HRH3PRKCIACHEHDAC8HDAC6 | |
| SCHEMBL19621198 | 0.77 | SKP2 (0.44) | PKMMAPTALDH1A1THRB | |
| SCHEMBL6138207 | 0.76 | GAA (0.48) | HPGDALOX15MAPTKDM4EMEN1 | |
| SCHEMBL27707407 | 0.75 | SKP2 (0.55) | HRH3PRKCIACHEHDAC8HDAC6 | |
| SCHEMBL2043393 | 0.72 | HRH3 (0.61) | HRH3ACHEHDAC8HDAC6HPGD | |
| SCHEMBL17450407 | 0.71 | ALDH1A1 (0.62) | HRH3ACHEPKMALOX15MEN1 | |
| SCHEMBL11623056 | 0.71 | HRH3 (0.46) | HRH3PRKCIACHEHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |