Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20961917 | 0.82 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL13638852 | 0.78 | HRH3 (0.44) | HRH3HDAC8HDAC6ACHEKDM4E | |
| SCHEMBL917999 | 0.78 | CDK1 (0.56) | HRH3HDAC8HDAC6ACHEKDM4E | |
| SCHEMBL13638842 | 0.75 | GRM2 (0.39) | ACHEMAPTBCHE | |
| SCHEMBL13638747 | 0.72 | HRH3 (0.40) | HRH3ALDH1A1KMT2A | |
| SCHEMBL2043393 | 0.70 | HRH3 (0.61) | HRH3HDAC8HDAC6ACHEALDH1A1 | |
| SCHEMBL13609382 | 0.70 | SRC (0.46) | KDM4EALDH1A1POLBMAPTTHRB | |
| SCHEMBL5583454 | 0.68 | ALDH1A1 (0.48) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL3633618 | 0.68 | ALDH1A1 (0.40) | HRH3HDAC8HDAC6ACHEMEN1 | |
| SCHEMBL13638748 | 0.68 | ADORA2A (0.35) | HDAC6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |