SCHEMBL6138207

SCHEMBL6138207

Nc1ccc(Cc2ccc(N)c(C=O)c2)cc1C=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.48
CYP3A4 P08684 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
RAB9A P51151 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 4/20 0.47
CDC25B P30305 1/20 0.47
CASP6 P55212 1/20 0.47
RCE1 Q9Y256 1/20 0.47
TSHR P16473 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CDK1 P06493 1/20 0.40
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17737226 0.89 CYP17A1 (0.56) GAACYP3A4KDM4EMAPTRAB9A
SCHEMBL12012867 0.83 SMN1; SMN2 (0.40) GAAKDM4EMAPTRAB9AMEN1
SCHEMBL19621198 0.80 SKP2 (0.44) MAPTRAB9AALDH1A1HSD17B10CDK1
SCHEMBL13638852 0.76 HRH3 (0.44) KDM4EMAPTMEN1KMT2APOLB
SCHEMBL18373342 0.75 CDK1 (0.58) ALOX15CDK1CA2
SCHEMBL19604355 0.75 CDK1 (0.33) GAAKDM4EMAPTKMT2AALDH1A1
SCHEMBL25917039 0.75 IDH1 (0.47) GAACYP3A4KDM4EMAPTRAB9A
SCHEMBL9404722 0.75 TDP1 (0.48) CYP3A4KDM4EMAPTMEN1KMT2A
SCHEMBL135290 0.75 TDP1 (0.40) CYP3A4MAPTRAB9AMEN1KMT2A
SCHEMBL283097 0.74 CDK1 (0.69) CDK1CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1258509-B1 Solventless polyimide silicone resin compositions SHINETSU CHEMICAL CO (JP) 2005-07-27 EP disclosed
US-6706841-B2 RECURRING UNITS OF AN AROMATIC TETRACARBOXYLIC ACID, AN AROMATIC AMINE AND AMINO FUNCTIONALIZED POLYSILOXANE, A (METH) ACRYLIC COMPOUND, AND A POLYMERIZATION INITIATOR HAS FLUIDITY AT 25 DEGREES C SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-03-16 US disclosed
US-20020188069-A1 Solventless polyimide silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-12-12 US disclosed
EP-1258509-A1 Solventless polyimide silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-11-20 EP disclosed
EP-0483376-B1 POLYIMIDE RESIN FILM KANEGAFUCHI CHEMICAL IND (JP) 1997-01-29 EP disclosed
US-5300619-A Dimensinal stability: high density packaging of electronics KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1994-04-05 US disclosed
EP-0483376-A1 POLYIMIDE RESIN FILM KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-05-06 EP disclosed