Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12395454 | 0.78 | RAB9A (0.48) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL7676025 | 0.77 | ERN1 (0.47) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL23667707 | 0.76 | TDP1 (0.50) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL21417199 | 0.76 | ERN1 (0.46) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL16741207 | 0.76 | ERN1 (0.46) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL1960577 | 0.76 | TYR (0.61) | ERN1TRIM24TYRTRIM33LMNA | |
| SCHEMBL12641406 | 0.75 | TAAR1 (0.39) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL12878040 | 0.74 | ALDH1A1 (0.59) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL13062022 | 0.73 | CDK1 (0.47) | KMT2A | |
| SCHEMBL17967100 | 0.72 | CDK1 (0.59) | ERN1TRIM24TYRTRIM33LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |