Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638804 | 0.91 | RAB9A (0.62) | RAB9AALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL13162010 | 0.84 | BRAF (0.71) | RAB9AALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL13638855 | 0.84 | NAMPT (0.59) | RAB9AALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL13162554 | 0.83 | RAB9A (0.64) | RAB9AALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL13162340 | 0.81 | BRAF (0.79) | RAB9AALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL13162550 | 0.81 | RAB9A (0.64) | RAB9AALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL13163080 | 0.79 | NPC1 (0.63) | RAB9AALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL3937459 | 0.78 | BRAF (0.84) | RAB9AALDH1A1POLBKMT2ABRAF | |
| SCHEMBL13163083 | 0.77 | MAPT (0.60) | RAB9AALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL11129936 | 0.77 | RAB9A (1.00) | RAB9AALDH1A1POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |