Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638739 | 0.84 | GRM2 (0.42) | GRM2PDE1BJAK2JAK1ALDH1A1 | |
| SCHEMBL13163941 | 0.76 | ALDH1A1 (0.53) | GRM2PDE1BJAK2JAK1ALDH1A1 | |
| SCHEMBL13634408 | 0.74 | GRM2 (0.43) | GRM2PDE1BJAK2JAK1ALDH1A1 | |
| SCHEMBL2561365 | 0.73 | GRM2 (0.42) | GRM2PDE1BJAK2JAK1ALDH1A1 | |
| SCHEMBL18291608 | 0.73 | PDE1B (0.44) | GRM2PDE1BJAK2JAK1PIK3CD | |
| SCHEMBL13162600 | 0.72 | KMT2A (0.49) | GRM2PDE1BJAK2JAK1ALDH1A1 | |
| SCHEMBL6132960 | 0.72 | JAK2 (0.44) | GRM2PDE1BJAK2JAK1ALDH1A1 | |
| SCHEMBL13164038 | 0.72 | GRM2 (0.45) | GRM2PDE1BJAK2JAK1SMN1; SMN2 | |
| SCHEMBL13162328 | 0.72 | ALDH1A1 (0.37) | GRM2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13270156 | 0.70 | ALDH1A1 (0.36) | GRM2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |