Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 12/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270611 | 0.88 | AR (0.44) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13162279 | 0.87 | AR (0.47) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13162764 | 0.81 | MTOR (0.41) | — | |
| SCHEMBL13162281 | 0.81 | MAPT (0.37) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3549078 | 0.80 | SMN1; SMN2 (0.36) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13161927 | 0.79 | NPC1 (0.36) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3549732 | 0.79 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13161918 | 0.78 | AR (0.31) | LMNAARNPC1RAB9A | |
| SCHEMBL13162283 | 0.78 | LMNA (0.37) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13161925 | 0.77 | ALDH1A1 (0.32) | ARNPC1RAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |