Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162283 | 0.85 | LMNA (0.37) | SMN1; SMN2RAB9ANPC1LMNAAR | |
| SCHEMBL13270611 | 0.82 | AR (0.44) | SMN1; SMN2RAB9ANPC1LMNAAR | |
| SCHEMBL13162279 | 0.81 | AR (0.47) | SMN1; SMN2RAB9ANPC1LMNAAR | |
| SCHEMBL13162281 | 0.81 | MAPT (0.37) | SMN1; SMN2RAB9ANPC1LMNAHRH3 | |
| SCHEMBL13638865 | 0.80 | LMNA (0.52) | SMN1; SMN2RAB9ANPC1LMNAAR | |
| SCHEMBL13161927 | 0.79 | NPC1 (0.36) | SMN1; SMN2RAB9ANPC1LMNAHRH3 | |
| SCHEMBL458365 | 0.76 | HRH3 (0.48) | SMN1; SMN2RAB9ANPC1LMNAHRH3 | |
| SCHEMBL13162277 | 0.76 | AR (0.34) | SMN1; SMN2RAB9ANPC1LMNAHRH3 | |
| SCHEMBL13161907 | 0.76 | RAB9A (0.37) | SMN1; SMN2RAB9ANPC1HRH3AR | |
| SCHEMBL13162773 | 0.76 | MTOR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | SMN1; SMN2 3601/4885RAB9A 4401/4885NPC1 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.