Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638975 | 0.82 | MAOA (0.39) | MAOAACHEALDH1A1TP53GAA | |
| SCHEMBL13162295 | 0.79 | MAOA (0.41) | MAOAACHEALDH1A1GAARAB9A | |
| SCHEMBL13634367 | 0.78 | PDE10A (0.35) | ALDH1A1TP53GAARAB9A | |
| SCHEMBL31482222 | 0.76 | MAOA (0.43) | MAOAACHEALDH1A1RAB9AMEN1 | |
| SCHEMBL15348901 | 0.75 | MAOA (0.40) | MAOAACHEALDH1A1GAARAB9A | |
| SCHEMBL13162285 | 0.73 | MAOA (0.40) | MAOAACHEALDH1A1GAARAB9A | |
| SCHEMBL13162299 | 0.73 | MAOA (0.40) | MAOAACHEALDH1A1GAARAB9A | |
| SCHEMBL31482190 | 0.72 | MAOA (0.39) | MAOAACHEALDH1A1RAB9AMEN1 | |
| SCHEMBL11011001 | 0.72 | MAOA (0.39) | MAOAACHEALDH1A1GAARAB9A | |
| SCHEMBL13634421 | 0.71 | PPARG (0.41) | GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |