Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | SLC12A5 | Q9H2X9 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638878 | 0.78 | MAOA (0.38) | ALDH1A1TP53GAARAB9A | |
| SCHEMBL13634421 | 0.78 | PPARG (0.41) | GAACYP2D6 | |
| SCHEMBL18674691 | 0.75 | ALDH1A1 (0.35) | SLC12A5LMNAALDH1A1TP53GAA | |
| SCHEMBL13634391 | 0.75 | NOS1 (0.34) | SLC12A5LMNAALDH1A1GAACYP2D6 | |
| SCHEMBL13634342 | 0.73 | NOS1 (0.38) | HRH3SLC12A5LMNAALDH1A1RAB9A | |
| SCHEMBL25933244 | 0.73 | SMN1; SMN2 (0.38) | SLC12A5LMNAALDH1A1GAARAB9A | |
| SCHEMBL3506347 | 0.72 | MAPK1 (0.42) | SLC12A5LMNAALDH1A1GAACYP2D6 | |
| SCHEMBL22837835 | 0.70 | LSS (0.47) | HRH3ALDH1A1TOP2ACYP2D6 | |
| SCHEMBL3556009 | 0.69 | NOS1 (0.34) | SLC12A5LMNAALDH1A1GAARAB9A | |
| SCHEMBL232983 | 0.69 | SMN1; SMN2 (0.40) | SLC12A5LMNAALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |