Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162295 | 0.86 | MAOA (0.41) | MAOAACHEMEN1KMT2AMAPT | |
| SCHEMBL13638878 | 0.82 | MAOA (0.38) | MAOAACHEMEN1KMT2AMAPT | |
| SCHEMBL15348901 | 0.81 | MAOA (0.40) | MAOAACHEMEN1KMT2AMAPT | |
| SCHEMBL13162299 | 0.79 | MAOA (0.40) | MAOAACHEMEN1KMT2AMAPT | |
| SCHEMBL13162285 | 0.79 | MAOA (0.40) | MAOAACHEMEN1KMT2AMAPT | |
| SCHEMBL11011001 | 0.78 | MAOA (0.39) | MAOAACHEMEN1KMT2AMAPT | |
| SCHEMBL15888636 | 0.75 | L3MBTL1 (0.41) | ACHEALDH1A1POLBKDM4E | |
| SCHEMBL13634391 | 0.74 | NOS1 (0.34) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL22335788 | 0.72 | CYP4A11 (0.45) | MAOAACHEMEN1KMT2AMAPT | |
| SCHEMBL13162766 | 0.72 | CSF1R (0.43) | MAOAACHEKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |