Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634857 | 0.94 | GPR6 (0.39) | KMT2AOPRK1IRAK4GPR6PDE4B | |
| SCHEMBL13634753 | 0.90 | OPRK1 (0.39) | KMT2AOPRK1IRAK4GPR6 | |
| SCHEMBL2770473 | 0.89 | KMT2A (0.44) | KMT2AOPRK1IRAK4PDE4BWNT3A | |
| SCHEMBL13638885 | 0.86 | IRAK4 (0.47) | KMT2AOPRK1IRAK4 | |
| SCHEMBL13634567 | 0.83 | MCHR1 (0.39) | KMT2AOPRK1IRAK4PDE4B | |
| SCHEMBL13638826 | 0.83 | MCHR1 (0.40) | KMT2AOPRK1 | |
| SCHEMBL13638933 | 0.82 | MCHR1 (0.39) | KMT2A | |
| SCHEMBL13634684 | 0.82 | MCHR1 (0.39) | IRAK4WNT3A | |
| SCHEMBL2772498 | 0.82 | PARP1 (0.43) | KMT2AOPRK1IRAK4PDE4B | |
| SCHEMBL13634599 | 0.81 | GPR6 (0.37) | KMT2AOPRK1GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |