Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634857 | 0.90 | GPR6 (0.39) | OPRK1KMT2AIRAK4GPR6SCD | |
| SCHEMBL13638910 | 0.90 | KMT2A (0.38) | OPRK1KMT2AIRAK4GPR6 | |
| SCHEMBL2770731 | 0.88 | OPRK1 (0.42) | OPRK1KMT2AIRAK4 | |
| SCHEMBL13634783 | 0.83 | IRAK4 (0.48) | OPRK1KMT2AIRAK4 | |
| SCHEMBL13634541 | 0.81 | OPRK1 (0.40) | OPRK1KMT2AIRAK4 | |
| SCHEMBL2772028 | 0.81 | OPRK1 (0.42) | OPRK1KMT2AIRAK4 | |
| Hydrochloric Acid SCHEMBL2770260 | 0.81 | OPRK1 (0.41) | OPRK1KMT2AIRAK4GSK3B | |
| SCHEMBL2772498 | 0.80 | PARP1 (0.43) | OPRK1KMT2AIRAK4 | |
| SCHEMBL2769972 | 0.80 | PIM1 (0.42) | GPR6SCDPIM1PIM3PIM2 | |
| Hydrochloric Acid SCHEMBL2770518 | 0.79 | IRAK4 (0.39) | OPRK1KMT2AIRAK4SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |