Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634910 | 0.94 | PIN1 (0.35) | PIN1IRAK4CHEK1FGFR1HRH3 | |
| SCHEMBL13162734 | 0.90 | PIN1 (0.34) | PIN1IRAK4CHEK1HRH3NAPEPLD | |
| SCHEMBL13638837 | 0.89 | SCD (0.40) | PIN1NAPEPLDSCDSCD5 | |
| SCHEMBL13638952 | 0.88 | CHEK1 (0.37) | PIN1CHEK1MAPK1 | |
| SCHEMBL2773656 | 0.88 | KDM4E (0.43) | KMT2AMEN1 | |
| SCHEMBL13639003 | 0.87 | PIN1 (0.37) | PIN1CHEK1HRH3NAPEPLDSCD | |
| SCHEMBL2770606 | 0.86 | PIN1 (0.37) | PIN1CHEK1HRH3NAPEPLDSCD | |
| SCHEMBL2770504 | 0.86 | PIN1 (0.37) | PIN1CHEK1HRH3NAPEPLDSCD | |
| SCHEMBL15888680 | 0.85 | PIN1 (0.36) | PIN1CHEK1HRH3NAPEPLDSCD | |
| SCHEMBL13163170 | 0.85 | PIN1 (0.36) | PIN1CHEK1HRH3NAPEPLDSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |