Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.32 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638923 | 0.94 | PIN1 (0.35) | PIN1IRAK4CHEK1FGFR1HRH3 | |
| SCHEMBL13634577 | 0.90 | PIN1 (0.34) | PIN1GLSIRAK4GPR6SCD | |
| SCHEMBL13634658 | 0.89 | GLS (0.40) | PIN1GLSNAPEPLDSCDSCD5 | |
| SCHEMBL13634773 | 0.88 | CHEK1 (0.37) | PIN1CHEK1 | |
| SCHEMBL13634933 | 0.88 | PDE4B (0.41) | — | |
| SCHEMBL13634760 | 0.87 | GLS (0.40) | PIN1GLSCHEK1GPR6HRH3 | |
| SCHEMBL13634751 | 0.86 | GLS (0.39) | PIN1GLSCHEK1GPR6HRH3 | |
| SCHEMBL13634924 | 0.86 | GLS (0.39) | PIN1GLSCHEK1GPR6HRH3 | |
| SCHEMBL13634578 | 0.85 | GLS (0.39) | PIN1GLSCHEK1GPR6HRH3 | |
| SCHEMBL13634918 | 0.85 | GLS (0.39) | PIN1GLSCHEK1GPR6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |