Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162671 | 0.91 | TSHR (0.44) | TSHRNTRK1SMN1; SMN2KDM1AKMT2A | |
| SCHEMBL13162025 | 0.89 | TSHR (0.43) | TSHRNTRK1SMN1; SMN2KDM1AKMT2A | |
| SCHEMBL13163132 | 0.79 | POLB (0.52) | TSHRSMN1; SMN2KMT2AMAPK14P2RX7 | |
| SCHEMBL13161961 | 0.78 | TSHR (0.47) | TSHRSMN1; SMN2KDM1AKMT2AP2RX7 | |
| SCHEMBL13162538 | 0.78 | NTRK1 (0.40) | TSHRNTRK1KDM1ANPC1RAB9A | |
| SCHEMBL13162043 | 0.77 | KDM4E (0.59) | TSHRSMN1; SMN2KMT2AMAPK14NPC1 | |
| SCHEMBL13634274 | 0.77 | ALDH1A1 (0.50) | NTRK1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL13162375 | 0.76 | KDM4E (0.55) | TSHRSMN1; SMN2KMT2AP2RX7NPC1 | |
| SCHEMBL13638862 | 0.76 | NTRK1 (0.39) | NTRK1KDM1ANPC1RAB9ASMYD3 | |
| SCHEMBL13162872 | 0.76 | TSHR (0.53) | TSHRSMN1; SMN2KDM1AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |