Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163923 | 0.90 | ALDH1A1 (0.48) | ALDH1A1NTRK1MAPTLMNABRD4 | |
| SCHEMBL2770947 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAPOLBBRD4 | |
| SCHEMBL13162753 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNANPC1RAB9ASIRT6 | |
| SCHEMBL13634152 | 0.78 | SIRT6 (0.51) | ALDH1A1MAPTLMNATDP1L3MBTL1 | |
| SCHEMBL2770068 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL13162755 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL13634183 | 0.77 | ALDH1A1 (0.49) | ALDH1A1POLBNPC1RAB9ASIGMAR1 | |
| SCHEMBL13638929 | 0.77 | TSHR (0.44) | NTRK1POLBBRD4NPC1RAB9A | |
| SCHEMBL13162671 | 0.77 | TSHR (0.44) | NTRK1POLBBRD4NPC1RAB9A | |
| SCHEMBL13162538 | 0.76 | NTRK1 (0.40) | ALDH1A1NTRK1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |