Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 3/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634646 | 0.93 | IRAK4 (0.43) | IRAK4NTRK1NAPEPLDFLT3MCHR1 | |
| SCHEMBL13270595 | 0.83 | IRAK4 (0.44) | IRAK4F10NTRK1NAPEPLDMCHR1 | |
| SCHEMBL13634551 | 0.81 | IRAK4 (0.47) | IRAK4NAPEPLDMCHR1P2RX7 | |
| SCHEMBL13634550 | 0.77 | IRAK4 (0.46) | IRAK4F10MCHR1P2RX7 | |
| SCHEMBL13634629 | 0.77 | GRM2 (0.40) | IRAK4F10FLT3MCHR1 | |
| SCHEMBL13162423 | 0.76 | JAK2 (0.39) | IRAK4F10NTRK1NAPEPLDFLT3 | |
| SCHEMBL13162062 | 0.76 | IRAK4 (0.43) | IRAK4F10NAPEPLD | |
| SCHEMBL13270421 | 0.75 | IRAK4 (0.45) | IRAK4FLT3MCHR1P2RX7 | |
| SCHEMBL13638812 | 0.74 | GPR6 (0.39) | IRAK4FLT3MCHR1P2RX7 | |
| SCHEMBL13638815 | 0.74 | MCHR1 (0.43) | IRAK4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |