Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 3/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PAICS | P22234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634670 | 0.93 | PARP1 (0.38) | GPR6TYK2IRAK4MCHR1MET | |
| SCHEMBL13638815 | 0.85 | MCHR1 (0.43) | GPR6IRAK4MCHR1 | |
| SCHEMBL13638986 | 0.85 | KMT2A (0.42) | NPC1RAB9A | |
| SCHEMBL13638901 | 0.85 | KMT2A (0.42) | NPC1RAB9A | |
| SCHEMBL13634779 | 0.84 | MCHR1 (0.43) | GPR6IRAK4MCHR1 | |
| SCHEMBL13634601 | 0.83 | MCHR1 (0.43) | GPR6IRAK4NPC1RAB9AMCHR1 | |
| SCHEMBL13634792 | 0.80 | PDE10A (0.46) | GPR6IRAK4PIM1PAICS | |
| SCHEMBL13634671 | 0.80 | PDE10A (0.46) | GPR6IRAK4PIM1PAICS | |
| SCHEMBL13634635 | 0.79 | PIM1 (0.45) | GPR6IRAK4PIM1 | |
| SCHEMBL13270419 | 0.79 | F10 (0.40) | IRAK4NPC1RAB9AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |