Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634742 | 0.91 | KMT2A (0.45) | GRM2IRAK4DRD4KDM4EKMT2A | |
| SCHEMBL13634900 | 0.91 | GRM2 (0.42) | GRM2IRAK4DRD4MDM2SMN1; SMN2 | |
| SCHEMBL13634943 | 0.91 | GRM2 (0.42) | GRM2IRAK4DRD4SMN1; SMN2S1PR1 | |
| SCHEMBL13634551 | 0.83 | IRAK4 (0.47) | IRAK4MCHR1KDM4E | |
| SCHEMBL13634550 | 0.81 | IRAK4 (0.46) | GRM2IRAK4MCHR1KDM4EF10 | |
| SCHEMBL13270595 | 0.79 | IRAK4 (0.44) | IRAK4MCHR1F10 | |
| SCHEMBL13638815 | 0.79 | MCHR1 (0.43) | IRAK4MCHR1DRD4 | |
| SCHEMBL13270421 | 0.79 | IRAK4 (0.45) | IRAK4MCHR1FLT3TYRO3MERTK | |
| SCHEMBL13634779 | 0.78 | MCHR1 (0.43) | IRAK4MCHR1 | |
| SCHEMBL13634777 | 0.77 | P2RX3 (0.44) | MCHR1FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |