Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | S100B | P04271 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429164 | 0.90 | SKP2 (0.55) | SKP2ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL14661925 | 0.85 | ALDH1A1 (0.43) | SKP2ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL8750664 | 0.82 | NPC1 (0.36) | SKP2ALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL31224895 | 0.81 | TSHR (0.54) | SKP2ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL18713938 | 0.80 | SKP2 (0.53) | SKP2ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL11970164 | 0.79 | GAA (0.57) | ALDH1A1CYP3A4TSHRESR1AR | |
| SCHEMBL11362457 | 0.78 | ALDH1A1 (0.42) | SKP2ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL7747249 | 0.77 | SKP2 (0.64) | SKP2ALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL14426661 | 0.77 | IDO1 (0.41) | ALDH1A1TSHRMEN1KMT2APOLB | |
| Orthotolidine SCHEMBL2812114 | 0.76 | ALDH1A1 (0.71) | SKP2ALDH1A1CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |