Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | S100B | P04271 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27496376 | 0.87 | SKP2 (0.56) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL237201 | 0.83 | SKP2 (0.61) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL31079561 | 0.83 | SKP2 (0.61) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL841783 | 0.83 | SKP2 (0.73) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL31634603 | 0.83 | SKP2 (0.73) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL7747145 | 0.82 | SKP2 (0.78) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL5683375 | 0.81 | SKP2 (0.46) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL6223652 | 0.81 | SKP2 (0.59) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| Ammonia Solution, Strong SCHEMBL22344976 | 0.81 | SKP2 (0.59) | SKP2CYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL3482834 | 0.81 | SKP2 (0.70) | SKP2CYP3A4ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113813982-A | Integral N-modified TS-1 catalyst carrier and preparation method thereof | 华东理工大学 | 2021-12-21 | — | — | CN | claimed |
| CN-113396137-A | Method for producing 1,1, 1-trifluoro-2, 2-bisarylethane, and 1,1, 1-trifluoro-2, 2-bisarylethane | 中央硝子株式会社 | 2021-09-14 | — | — | CN | claimed |
| WO-2025049824-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES | OSMO LABS, PBC (US) | 2025-03-06 | — | — | WO | disclosed |
| US-20240383914-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE | JANSSEN PHARMACEUTICA NV (BE) | 2024-11-21 | — | — | US | disclosed |
| US-12065446-B2 | Inhibitors of Bruton's tyrosine kinase and method of their use | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-20 | — | — | US | disclosed |
| CN-114621118-B | Lignin-based diphenylmethane diisocyanate and application thereof in preparation of polyurethane material | 南京工业大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-115650861-B | Application of lignin-based polyurethane chain extender in preparation of polyurethane material | 南京工业大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-113412299-B | Polyamic acid and polyimide, optical film and display device, and method for producing same | 中央硝子株式会社 | 2023-08-18 | — | — | CN | disclosed |
| CN-116194435-A | Fluorine-containing diamine or salt thereof, method for producing fluorine-containing diamine or salt thereof, polyamide, method for producing polyamide, polyamide solution, polyamide cyclized body, method for producing polyamide cyclized body, insulating material for high-frequency electronic component, method for producing insulating material for high-frequency electronic component, high-frequency machine, and insulating material for producing high-frequency electronic component | 中央硝子株式会社 | 2023-05-30 | — | — | CN | disclosed |
| US-20230159534-A1 | ADENOSINE RECEPTOR ANTAGONIST COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-05-25 | — | — | US | disclosed |
| US-20230097422-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | US | disclosed |
| US-4326075-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4297297-A | α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates | ZOECON CORP. (US) | 1981-10-27 | — | — | US | disclosed |
| US-4266056-A | FUNGICIDES, BACTERICIDES | ZOECON CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4203920-A | ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4173645-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |
| EP-0003101-A1 | Substituted N-cyclohexyl isothiourea, their preparation and their use as pesticides | BAYER AG (DE) | 1979-07-25 | — | — | EP | disclosed |
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12065446-B2 | Inhibitors of Bruton's tyrosine kinase and method of their use | ABL1, BTK, LYN | SKP2 747/4885CYP3A4 3311/4885ALDH1A1 4036/4885 |
| US-20230159534-A1 | ADENOSINE RECEPTOR ANTAGONIST COMPOUNDS | ADORA2A, ADORA1, ADORA3 | SKP2 2343/4885CYP3A4 4559/4885ALDH1A1 1415/4885 |
| US-20240383914-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE | ABL1, BTK, MYLK2 | SKP2 752/4885CYP3A4 3769/4885ALDH1A1 3938/4885 |
| US-20230097422-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE | ABL1, BTK, LYN | SKP2 747/4885CYP3A4 3311/4885ALDH1A1 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.