Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638901 | 1.00 | KMT2A (0.42) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13634611 | 0.93 | POLB (0.42) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13634610 | 0.93 | POLB (0.42) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13634675 | 0.86 | PDE10A (0.48) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13634542 | 0.85 | POLB (0.44) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13638812 | 0.85 | GPR6 (0.39) | NPC1RAB9A | |
| SCHEMBL13634670 | 0.78 | PARP1 (0.38) | KMT2AMEN1 | |
| SCHEMBL13638762 | 0.76 | PDE10A (0.40) | MAPTALDH1A1HPGDKDM4EAXL | |
| SCHEMBL13634801 | 0.76 | CNR1 (0.46) | CYP2C9CYP2C19MAPT | |
| SCHEMBL13270762 | 0.75 | S1PR1 (0.40) | SMN1; SMN2TSHRMAPK1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |