Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PAICS | P22234 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638812 | 0.93 | GPR6 (0.39) | GPR6TYK2IRAK4METGRM5 | |
| SCHEMBL13634610 | 0.84 | POLB (0.42) | MEN1KMT2A | |
| SCHEMBL13634611 | 0.84 | POLB (0.42) | MEN1KMT2A | |
| SCHEMBL13638815 | 0.84 | MCHR1 (0.43) | GPR6IRAK4MCHR1 | |
| SCHEMBL13634779 | 0.84 | MCHR1 (0.43) | GPR6IRAK4MCHR1 | |
| SCHEMBL13634601 | 0.83 | MCHR1 (0.43) | PARP1GPR6IRAK4MCHR1KMT2A | |
| SCHEMBL13634792 | 0.81 | PDE10A (0.46) | GPR6IRAK4PAICSPIM1 | |
| SCHEMBL13634671 | 0.81 | PDE10A (0.46) | GPR6IRAK4PAICSPIM1 | |
| SCHEMBL13634551 | 0.81 | IRAK4 (0.47) | IRAK4P2RX7MCHR1 | |
| SCHEMBL13634502 | 0.80 | GPR6 (0.44) | GPR6TYK2IRAK4PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |