Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.40 |
| ▸ | GPR6 | P46095 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634500 | 0.93 | GPR6 (0.42) | PDE10AGPR6PAICSCNR1PIM1 | |
| SCHEMBL13634790 | 0.90 | PIM1 (0.41) | PDE10AGPR6PAICSCNR1PIM1 | |
| SCHEMBL13634676 | 0.87 | GPR6 (0.42) | PDE10AGPR6NAMPTPAICSCNR1 | |
| SCHEMBL13634596 | 0.85 | GPR6 (0.38) | GPR6PAICSKDM4EHPGDALDH1A1 | |
| SCHEMBL13634675 | 0.85 | PDE10A (0.48) | PDE10ANAMPTKDM4EHPGDMAPT | |
| SCHEMBL13638814 | 0.84 | PDE10A (0.41) | PDE10AGPR6NAMPTALDH1A1AXL | |
| SCHEMBL13634792 | 0.84 | PDE10A (0.46) | PDE10AGPR6NAMPTPAICSPIM1 | |
| SCHEMBL13634671 | 0.84 | PDE10A (0.46) | PDE10AGPR6NAMPTPAICSPIM1 | |
| SCHEMBL13638871 | 0.83 | TGFBR1 (0.36) | PDE10AGPR6PAICSCNR1PIM1 | |
| SCHEMBL13634512 | 0.83 | SCD (0.39) | PDE10AGPR6PAICSMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |