Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636812 | 0.91 | KIF11 (0.46) | NFE2L2KIF11APPKCNH2MAT2A | |
| SCHEMBL13978808 | 0.88 | NFE2L2 (0.52) | NFE2L2TUBB1APPKCNH2MAT2A | |
| SCHEMBL13636757 | 0.80 | PTGS1 (0.45) | NFE2L2TUBB1APPKCNH2MAT2A | |
| SCHEMBL13978824 | 0.78 | APP (0.49) | NFE2L2KIF11APPPTGS1PTGS2 | |
| SCHEMBL13636779 | 0.73 | PTGS1 (0.40) | NFE2L2TUBB1APPKCNH2MAT2A | |
| SCHEMBL10015732 | 0.72 | TUBB1 (0.49) | NFE2L2TUBB1APPMAPTALOX5 | |
| SCHEMBL13978801 | 0.72 | TUBB1 (0.49) | NFE2L2TUBB1APPMAPTALOX5 | |
| SCHEMBL14569993 | 0.72 | NFE2L2 (0.74) | NFE2L2TUBB1ALOX5PTGS1PTGS2 | |
| SCHEMBL13463210 | 0.72 | NFE2L2 (0.74) | NFE2L2TUBB1ALOX5PTGS1PTGS2 | |
| SCHEMBL13636747 | 0.72 | NFE2L2 (0.62) | NFE2L2TUBB1APPKCNH2MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | NFE2L2 423/4885KIF11 1688/4885TUBB1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.