Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308253 | 0.86 | FDPS (0.47) | SMN1; SMN2ALDH1A1RAB9AKMT2AFDPS | |
| SCHEMBL5070274 | 0.82 | THRA (0.52) | THRATHRBHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1017821 | 0.77 | HTT (0.51) | THRATHRBHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9672930 | 0.75 | THRB (0.56) | THRATHRBHTTALDH1A1RAB9A | |
| SCHEMBL6477081 | 0.74 | THRA (0.54) | THRATHRBHTTPLA2G2APLA2G4B | |
| SCHEMBL504032 | 0.73 | HTT (0.55) | HTTSMN1; SMN2ALDH1A1RAB9ACA12 | |
| SCHEMBL10527851 | 0.72 | RARB (0.53) | HTTALDH1A1CA12CA2KMT2A | |
| SCHEMBL11573788 | 0.72 | THRA (0.60) | THRATHRBALDH1A1PLA2G2AKMT2A | |
| SCHEMBL7829330 | 0.71 | THRA (0.62) | THRATHRBALDH1A1KMT2APLA2G4B | |
| SCHEMBL22438945 | 0.71 | THRA (0.62) | THRATHRBALDH1A1KMT2APLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |