Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.50 |
| ▸ | MMP13 | P45452 | 10/20 | 0.50 |
| ▸ | MMP9 | P14780 | 8/20 | 0.50 |
| ▸ | MMP1 | P03956 | 8/20 | 0.50 |
| ▸ | MMP8 | P22894 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 8/20 | 0.49 |
| ▸ | MMP7 | P09237 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639192 | 1.00 | MMP2 (0.50) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL7357601 | 0.90 | MMP2 (0.52) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL13639185 | 0.88 | MMP2 (0.57) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL13643222 | 0.88 | MMP2 (0.57) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL13639186 | 0.88 | MMP2 (0.48) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL7347534 | 0.88 | L3MBTL1 (0.55) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL13639190 | 0.88 | MMP2 (0.48) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL7347538 | 0.88 | L3MBTL1 (0.55) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL1499947 | 0.88 | MMP2 (0.50) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL7348211 | 0.88 | L3MBTL1 (0.55) | MMP2MMP13MMP9MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520573-A1 | Compounds with matrix-metalloproteinase inhibitory activity | Westfälische Wilhelms-Universität Münster (DE) | 2012-11-07 | — | — | EP | disclosed |