Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639328 | 0.91 | IL6 (0.55) | IL6FFAR1FFAR4MDM2 | |
| SCHEMBL13639334 | 0.89 | IL6 (0.54) | IL6MAPTABL1 | |
| SCHEMBL13639320 | 0.87 | IL6 (0.63) | IL6FFAR1FFAR4GRIN1GRIN2B | |
| SCHEMBL13639356 | 0.87 | IL6 (0.50) | IL6GRIN1GRIN2B | |
| SCHEMBL13639310 | 0.86 | IL6 (0.51) | IL6MAPTHTT | |
| SCHEMBL13639317 | 0.86 | IL6 (0.51) | IL6MAPTHTTSYK | |
| SCHEMBL4141576 | 0.86 | IL6 (0.81) | IL6FFAR1FFAR4GRIN1GRIN2B | |
| SCHEMBL13639295 | 0.85 | IL6 (0.53) | IL6FFAR1FFAR4GRIN1GRIN2B | |
| SCHEMBL1314920 | 0.83 | IL6 (0.55) | IL6 | |
| SCHEMBL13460051 | 0.81 | IL6 (0.50) | IL6MOGAT2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |