Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639295 | 0.90 | IL6 (0.53) | IL6FFAR1FFAR4GRIN1GRIN2B | |
| SCHEMBL13639328 | 0.88 | IL6 (0.55) | IL6FFAR1FFAR4 | |
| SCHEMBL13639301 | 0.87 | IL6 (0.60) | IL6FFAR1FFAR4GRIN1GRIN2B | |
| SCHEMBL13639334 | 0.85 | IL6 (0.54) | IL6ESR1 | |
| SCHEMBL13639316 | 0.84 | IL6 (0.57) | IL6GRIN1GRIN2BHTR2C | |
| SCHEMBL13639367 | 0.83 | IL6 (0.48) | IL6 | |
| SCHEMBL4582029 | 0.83 | IL6 (0.56) | IL6ESR1 | |
| SCHEMBL1917741 | 0.83 | IL6 (0.89) | IL6FFAR1FFAR4ESR1GRIN1 | |
| SCHEMBL4145214 | 0.83 | IL6 (0.46) | IL6GRIN1GRIN2B | |
| SCHEMBL4136269 | 0.82 | IL6 (0.47) | IL6GRIN1GRIN2BMOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |