Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015809 | 0.94 | IL6 (0.46) | IL6MEN1NPC1CASP3KMT2A | |
| SCHEMBL13639305 | 0.88 | MEN1 (0.33) | IL6MEN1NPC1CASP3KMT2A | |
| SCHEMBL13639303 | 0.87 | IL6 (0.47) | IL6KMT2APDCD1CD274PRNP | |
| SCHEMBL14015601 | 0.86 | IL6 (0.46) | IL6MEN1KMT2APRNPMAPT | |
| SCHEMBL13639304 | 0.84 | IL6 (0.54) | IL6 | |
| SCHEMBL13639348 | 0.84 | IL6 (0.44) | IL6KMT2A | |
| SCHEMBL13639351 | 0.83 | IL6 (0.46) | IL6KMT2APRNPMAPT | |
| SCHEMBL4580626 | 0.83 | IL6 (0.48) | IL6MEN1NPC1CASP3KMT2A | |
| SCHEMBL14015592 | 0.83 | IL6 (0.44) | IL6KMT2AMAPT | |
| SCHEMBL4132008 | 0.83 | IL6 (0.51) | IL6MEN1NPC1CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |