Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639307 | 0.87 | IL6 (0.59) | IL6 | |
| SCHEMBL14015569 | 0.86 | IL6 (0.55) | IL6KCNH2GRIN1GRIN2B | |
| SCHEMBL13639311 | 0.84 | IL6 (0.46) | IL6 | |
| SCHEMBL12533076 | 0.84 | IL6 (0.52) | IL6 | |
| SCHEMBL14015566 | 0.81 | IL6 (0.58) | IL6 | |
| SCHEMBL12533028 | 0.80 | IL6 (0.51) | IL6 | |
| SCHEMBL4135434 | 0.80 | IL6 (0.56) | IL6GRIN1GRIN2B | |
| SCHEMBL13639338 | 0.80 | IL6 (0.51) | IL6 | |
| SCHEMBL13478141 | 0.80 | IL6 (0.47) | IL6 | |
| SCHEMBL13639302 | 0.80 | IL6 (0.49) | IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |