Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.32 |
| ▸ | CDK9 | P50750 | 11/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12533076 | 0.89 | IL6 (0.52) | IL6 | |
| SCHEMBL14015566 | 0.87 | IL6 (0.58) | IL6CREBBPCCNT1CDK9 | |
| SCHEMBL13639304 | 0.87 | IL6 (0.54) | IL6 | |
| SCHEMBL12533028 | 0.85 | IL6 (0.51) | IL6 | |
| SCHEMBL13639302 | 0.84 | IL6 (0.49) | IL6 | |
| SCHEMBL13639338 | 0.84 | IL6 (0.51) | IL6 | |
| SCHEMBL13478141 | 0.84 | IL6 (0.47) | IL6 | |
| SCHEMBL13639303 | 0.83 | IL6 (0.47) | IL6 | |
| SCHEMBL13639351 | 0.83 | IL6 (0.46) | IL6 | |
| SCHEMBL14015601 | 0.82 | IL6 (0.46) | IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |