SCHEMBL13639413

SCHEMBL13639413

C1=CC2Nc3c(-c4ccccc4)cccc3C2C=C1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
DPP4 P27487 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24603889 0.75 MAPK14 (0.32)
SCHEMBL21740555 0.74 CHRNB2 (0.36) CHRNB2CHRNA4BRD4CREBBPDPP4
SCHEMBL12333958 0.73 TNKS2 (0.37)
SCHEMBL24727347 0.71 KDM4E (0.41)
SCHEMBL17573993 0.70 CHRNB2 (0.40) CHRNB2CHRNA4BRD4CREBBPDPP4
SCHEMBL454276 0.70 HSPA1A (0.38)
SCHEMBL19004692 0.70 HSPA1A (0.38)
SCHEMBL15704498 0.70 HSPA1A (0.38)
SCHEMBL22544445 0.69 KDM4E (0.33)
SCHEMBL17573743 0.68 CHRNB2 (0.38) CHRNB2CHRNA4BRD4CREBBPADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2521197-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-11-07 EP disclosed