SCHEMBL454276

SCHEMBL454276

C1=CC2Nc3ccccc3C2C=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA1A P0DMV8 1/20 0.38
PTPN7 P35236 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 6/20 0.36
KMT2A Q03164 6/20 0.36
MAPT P10636 5/20 0.36
GAA P10253 4/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 2/20 0.36
MCL1 Q07820 2/20 0.36
HSD17B10 Q99714 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PIM1 P11309 1/20 0.35
PBRM1 Q86U86 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15704498 1.00 HSPA1A (0.38) HSPA1APTPN7TDP1MEN1KMT2A
SCHEMBL19004692 1.00 HSPA1A (0.38) HSPA1APTPN7TDP1MEN1KMT2A
Acetic Acid SCHEMBL11557554 0.88 HSPA1A (0.44) HSPA1APTPN7TDP1KMT2AMAPT
SCHEMBL12333958 0.86 TNKS2 (0.37) KMT2AALDH1A1HPGDHSD17B10KDM4E
SCHEMBL8080080 0.77 MAPT (0.36) HSPA1APTPN7TDP1MEN1KMT2A
SCHEMBL21863161 0.77 MAOA (0.31) MAPTGAAMAPK1MAOARAB9A
SCHEMBL25971218 0.77 KDM4E (0.32) HSPA1APTPN7TDP1MEN1KMT2A
SCHEMBL24727347 0.77 KDM4E (0.41) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL20634086 0.77 KDM4E (0.39) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL8620692 0.77 CREBBP (0.37) MEN1KMT2AMAPTGAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861128-A Polymerizable compound and optically anisotropic body 江苏创拓新材料有限公司 2021-12-31 CN claimed
EP-1852420-B1 Indole compounds for treating respiratory disorders ONO PHARMACEUTICAL CO (JP) 2012-10-17 EP claimed
US-8153625-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2012-04-10 US claimed
US-20110280806-A1 DYE CONJUGATE IMAGING AGENTS GE HEALTHCARE AS (NO) 2011-11-17 US claimed
EP-2373349-A1 DYE CONJUGATE IMAGING AGENTS GE Healthcare AS (NO) 2011-10-12 EP claimed
WO-2010057944-A9 DYE CONJUGATE IMAGING AGENTS GE HEALTHCARE AS (NO) 2010-09-16 WO claimed
US-7759336-B2 Nitrogen-containing heterocyclic compounds and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2010-07-20 US claimed
WO-2010057944-A1 DYE CONJUGATE IMAGING AGENTS GE HEALTHCARE AS (NO) 2010-05-27 WO claimed
US-12600730-B2 Substituted cyclopenta[c]pyrroles as ABHD6 antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 2026-04-14 US disclosed
US-20260083735-A1 ABHD6 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2026-03-26 US disclosed
US-12535732-B2 Coloring composition, film, optical filter, solid-state imaging element and image display device FUJIFILM CORPORATION (JP) 2026-01-27 US disclosed
US-12529956-B2 Resin composition, film, optical filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2026-01-20 US disclosed
US-12529969-B2 Coloring composition, film, optical filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2026-01-20 US disclosed
US-12528947-B2 Infrared-absorbing composition, film, optical filter, solid-state imaging element, image display device, and infrared sensor FUJIFILM CORPORATION (JP) 2026-01-20 US disclosed
US-5892056-A THE RIGIDIFIED CHROMOPHORES HAVE NARROWED ABSORPTION BANDS RELATIVE TO CORRESPONDING NON-RIGID CHROMOPHORES. DYES PREPARED FROM THE DYE PRECURSORS OF THE INVENTION TYPICALLY HAVE GOOD SOLUBILITY IN NON-POLAR SOLVENTS. IMATION CORP. (US) 1999-04-06 US disclosed
EP-0010029-B1 ELLIPTICINES SUBSTITUTED IN POSITION 1 BY A POLYAMINE CHAIN, THEIR SYNTHESIS AND MEDICINES CONTAINING THEM ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1982-11-17 EP disclosed
US-4234487-A Process of making a carbazole acetic acid HOFFMANN-LA ROCHE INC. (US) 1980-11-18 US disclosed
EP-0010029-A2 Ellipticines substituted in position 1 by a polyamine chain, their synthesis and medicines containing them ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1980-04-16 EP disclosed
US-4179443-A ANTIINFLAMMATORY AGENTS, ANTIRHEUMATIC AGENTS, CHEMICAL INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 1979-12-18 US disclosed
US-4146542-A ANTIINFLAMMATORY AGENTS HOFFMANN-LA ROCHE INC. (US) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110280806-A1 DYE CONJUGATE IMAGING AGENTS DSC1, SDCBP, DOCK5 HSPA1A 3945/4885PTPN7 4145/4885TDP1 4020/4885
US-12535732-B2 Coloring composition, film, optical filter, solid-state imaging element and image display device SF1, RER1, SFXN1 HSPA1A 3321/4885PTPN7 1755/4885TDP1 2689/4885
US-12529969-B2 Coloring composition, film, optical filter, solid-state imaging element, image display device, and compound RER1, SEM1, SF1 HSPA1A 2698/4885PTPN7 2957/4885TDP1 2843/4885
US-12600730-B2 Substituted cyclopenta[c]pyrroles as ABHD6 antagonists ABHD6, ABHD16A, HDHD5 HSPA1A 783/4885PTPN7 2985/4885TDP1 1688/4885
US-12529956-B2 Resin composition, film, optical filter, solid-state imaging element, and image display device PTGER1, CD40, FPR1 HSPA1A 903/4885PTPN7 3828/4885TDP1 2343/4885
US-20260083735-A1 ABHD6 ANTAGONIST ABHD6, ABHD16A, ABHD12 HSPA1A 1676/4885PTPN7 3184/4885TDP1 3051/4885
US-12528947-B2 Infrared-absorbing composition, film, optical filter, solid-state imaging element, image display device, and infrared sensor CRY2, CRY1, CHRM1 HSPA1A 1195/4885PTPN7 1917/4885TDP1 2659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.